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Built on research. 
Connected to real life. 

“Why can’t I just check my insulin?”

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For our founder Maren, who lives with type 1 diabetes, this question was personal.

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It became the starting point for research at the Diabetes Center Berne and for LUMIQ.

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Today, we’re developing a simple way to check insulin quality, bringing together science and the everyday experience of living with diabetes.

Research behind the questions 

We are studying what happens to insulin under real-world conditions, and how changes in its biological activity could be detected.​​

Insulin activity in everyday life

​Experiences reported by people with type 1 diabetes, including challenges with storage and travel.​​​​

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​​​Hanne Ballhausen, Katarina Braune, Lutz Heinemann & Maren Schinz Journal of Diabetes Science and Technology · 2025

For people living with type 1 diabetes, insulin is essential - but keeping it at the right temperature can be challenging. A multinational survey found that nearly one in three people (32%) had experienced difficulties storing insulin while travelling, while 28% reported heat-related incidents. Everyday situations such as travel, hot weather, or leaving insulin in a warm environment can make proper storage challenging. These findings highlight a practical issue that can easily be overlooked: insulin needs to work in the real world, not just under ideal storage conditions. The study underscores the need for clearer guidance and practical solutions to help people with diabetes protect their insulin from heat and maintain its effectiveness wherever and whenever.

Predicting potency changes

Can insulin quality changes be predicted?
We are developing statistical models to better understand how stress conditions may affect insulin potency over time.

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Kokona DC, Caduff M, Dobitz S, Schinz M. Developing Statistical Models to Predict the Potency of Stressed Insulins. ATTD. 2026.

Understanding insulin degradation

What changes at the structural molecular level?
We investigate changes in insulin to better understand degradation, improve prediction of insulin stability.

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Kokona DC, Dobitz S, Schinz M, Balmer ML. Investigating Insulin Stability: Molecular Insights into Degradation Mechanisms and Structural Alterations for Predictive Stability Modelling and Therapeutic Optimization. GCB Symposium. 2026.

Insulin, temperature and the real world

​What research tells us about insulin stability and where real-world evidence is still needed.​​​​

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​​​Lutz Heinemann, Stefanie Dobitz & Maren Schinz
Journal of Diabetes Science and Technology · 2026

For people who rely on insulin to manage their diabetes, keeping their insulin at the right temperature is an important part of everyday life. But insulin can be exposed to heat, cold, or physical stress during travel, at home, outdoors, or while being transported. As the world gets warmer, these challenges are becoming increasingly important - particularly for people living in hot climates or places where reliable refrigeration is not always available. Our review explores what happens to insulin when it is exposed to temperatures outside the recommended range. Although we know from laboratory studies that temperature can affect insulin, we still have much to learn about what happens in real-life situations. Better understanding of these effects will help people with diabetes store and use their insulin safely, improve guidance, and support access to effective insulin in a changing climate.

Measuring insulin activity

Can we measure whether insulin still works as expected?
We developed laboratory methods to quantify the biological activity of thermally stressed insulin.

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Kokona CD, Dobitz S, Schinz M. Quantifying the Biological Activity of Thermally Stressed Insulins In Vitro. ATTD. 2026.

Bringing measurement to the point of use

What if insulin quality could be checked when it matters?
Our work explores a missing layer in diabetes care: direct measurement of insulin activity at the point of use.

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Schinz M, et al. The Missing Layer in Diabetes Care: Direct Measurement of Insulin Activity at the Point of Use. Breakthrough T1D CRC. 2026.

The research journey

Explore the insulin activity research featured by DCB, D-Journal and sitem-insel.

INSPIRE LAB

In the insulin spotlight.

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SITEM-INSEL SUCCESS STORY

Advancing insulin activity research with Beyond Diagnostics

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CONFERENCE RECAP

Insulin Insight Conference 2026

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DAY OF THE SICK 2024

A closer look at insulin research
Federal Councillor Viola Amherd visited the INSPIRE Lab on the Day of the Sick.

Insulin knowledge, made accessible

Independent resources on storage, travel and everyday questions

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Storage & travel

NHS · IDF Europe

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Everyday questions

diabetesDE · ÖDG

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Read in your language

d-journal·DE/FR

Follow the research. Help shape what comes next.

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